Hyperthyroidism in cats is one of the most common endocrine disorders seen in our feline friends, especially as they age. If left untreated, this condition can significantly affect a cat’s quality of life, leading to rapid weight loss, behavioral changes, and other serious health complications.
But what exactly is hyperthyroidism, and how can pet parents recognize the signs early on? In this article, we’ll break down the causes, symptoms, and treatment options, along with some prevention tips to help you ensure your furry companion stays happy and healthy.
What Is Hyperthyroidism?
Hyperthyroidism in cats occurs when one or both thyroid glands produce excessive thyroid hormones T3 and T4. These thyroid hormones affect a cat’s metabolism, causing an overactive thyroid that can lead to increased appetite, weight loss, and a range of other health problems.
Most cats develop hyperthyroidism due to abnormal thyroid tissue, specifically benign growths called adenomas on the thyroid glands. However, in rare cases, a malignant thyroid carcinoma can be the cause.
Feline hyperthyroidism is most frequently seen in older cats, with the average age of diagnosis typically falling between 12 and 13 years. It’s also worth noting that as the disease progresses, untreated hyperthyroid cats may experience complications like high blood pressure, kidney disease, or liver disease.
Causes of Hyperthyroidism in Cats
The exact cause of hyperthyroidism isn’t fully understood, but most cases are linked to benign growths known as adenomas in the thyroid glands. These growths cause the glands to overproduce thyroid hormones, leading to the symptoms we associate with hyperthyroidism.
Some potential factors that may contribute to this condition include:
Dietary Factors: Certain cat foods, particularly those containing excessive iodine, may play a role.
Environmental Toxins: Long-term exposure to certain chemicals found in household products or even cat food packaging could increase the risk.
Age: Hyperthyroidism is more common in older cats, indicating that age-related changes in thyroid function may play a role.
While these factors provide some clues, hyperthyroidism can still appear unexpectedly, even in cats with no clear risk factors.
Symptoms of Hyperthyroidism

Weight Loss Despite Increased Appetite
One of the most common signs of hyperthyroidism in cats is significant weight loss, even as the cat’s appetite increases dramatically. This is due to excessive thyroid hormone production by the overactive thyroid gland, which accelerates the cat’s body’s metabolic rate.
Increased Thirst and Urination
Hyperthyroid cats often drink more water and visit the litter box more frequently. These symptoms may also be linked to secondary conditions like kidney disease, which are sometimes associated with treating hyperthyroidism.
Restlessness or Hyperactivity
Cats with feline hyperthyroidism may show changes in behavior, including restlessness, more frequent vocalizations, or constant pacing. These symptoms result from elevated thyroid hormone levels affecting the cat's body and overall energy levels.
Poor Coat Condition
A hyperthyroid cat may develop a dull, unkempt coat, increased shedding, or other signs of poor grooming. These issues often worsen over a few weeks as the condition progresses.
Vomiting and Diarrhea
Some cats may develop gastrointestinal issues like vomiting and diarrhea, which are also common signs of hyperthyroidism.
Heart-Related Symptoms
Hyperthyroidism can strain the heart, leading to rapid heart rate, high blood pressure, or difficulty breathing. In severe cases, this can progress to heart disease if left untreated.
Diagnose Hyperthyroidism
Physical Exam
Diagnosing hyperthyroidism in cats involves several key steps that help confirm the presence of this common disease and evaluate the cat's overall health. The process typically begins with a detailed physical exam by your veterinarian.
Enlarged Thyroid Gland: Your vet will examine your cat's neck to check for an enlarged thyroid gland. This is often one of the first clinical signs of feline hyperthyroidism, as affected cats may develop growths on one or both of their two thyroid glands.
Heart Rate and Blood Pressure: Measuring heart rate and blood pressure is critical, as hyperthyroid cats often have high blood pressure, which can lead to complications like heart disease, heart failure, or even sudden blindness.
Once these initial checks are complete, your vet will perform diagnostic testing to confirm the condition.
Blood Test
A standard blood chemistry panel and complete blood count (CBC) will be performed to evaluate organ function and overall health. The key diagnostic test for cats diagnosed with hyperthyroidism symptoms is measuring thyroid hormone levels (T4). An elevated T4 level indicates an overactive thyroid gland, a hallmark of hyperthyroid disease.
Additional Tests
If your cat shows concurrent health issues, such as kidney disease, or if the disease progresses, further diagnostic tests may be necessary:
Thyroid Scan: Imaging can pinpoint abnormal thyroid tissue or detect thyroid carcinoma, a rare malignant form of thyroid disease.
Blood Pressure Monitoring: Consistent monitoring ensures your cat's blood pressure remains normal.
Urinalysis: Assesses kidney function and screens for underlying issues.
Treatment Options for Hyperthyroidism in Cats

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Hyperthyroidism in cats is one of the most common diseases affecting the thyroid gland, but the good news is that it is highly treatable! With advancements in veterinary medicine, there are several options for treating feline hyperthyroidism, depending on your cat’s overall health, average age, clinical signs, and the severity of the condition. Here are the main treatment approaches:
Medications
Anti-thyroid drugs, such as methimazole, are commonly used to manage thyroid hormone production. These oral medications effectively stabilize thyroid levels but require daily administration and regular blood work to ensure thyroid hormone levels stay within the normal range. This approach involves lifelong treatment and close monitoring of kidney function and other clinical signs for many cats diagnosed with hyperthyroidism.
Radioactive Iodine Therapy
Regarded as the most effective treatment for hyperthyroid cats, radioactive iodine therapy consists of a single injection of radioactive iodine (radioiodine treatment). This therapy targets the affected thyroid gland and destroys overactive thyroid tissue without harming nearby structures like the parathyroid glands. Most cats treated with radioactive iodine achieve normal hormone levels within a few weeks, making it a highly effective and often curative option. However, this treatment requires specialized facilities and isolates the cat’s body due to the radioactive substance used.
Surgical Treatment (Thyroidectomy)
For some hyperthyroid cats, surgical removal of the affected thyroid gland(s) is recommended. This option can effectively eliminate overactive thyroid tissue but may pose risks, such as low blood calcium levels if the parathyroid glands are inadvertently affected during the procedure. A thorough physical exam and pre-surgical evaluations are essential for cats undergoing surgical treatment.
Dietary Management
For cats who are not candidates for radioactive iodine treatment or surgical removal, dietary therapy can help manage hyperthyroidism. Prescription diets designed to limit iodine intake can help regulate thyroid hormone production and maintain thyroid levels within the normal range. This non-invasive approach may suit cats with concurrent conditions like kidney disease.
Preventing Hyperthyroidism in Cats
Hyperthyroidism in cats, a common disease affecting the thyroid gland, often occurs in older cats and is characterized by an enlarged thyroid gland and excessive thyroid hormone production. While preventing feline hyperthyroidism entirely is challenging, there are strategies to minimize risks and promote your cat’s overall well-being.
Feed a Balanced Diet
A high-quality diet with appropriate iodine levels can help regulate thyroid hormone production. Avoid diets heavily reliant on fish, which may contain excess iodine, and consider dietary therapy for cats diagnosed with thyroid disease. This treatment helps regulate hormone levels and lowers the risk of developing hyperthyroidism. Regular monitoring of your cat’s dietary intake can also contribute to healthy thyroid tissue and decreased incidence of hyperthyroidism.
Minimize Chemical Exposure
Thyroid gland issues have been associated with exposure to household chemicals, pesticides, and other environmental toxins. Limiting these exposures can help reduce the risk of thyroid disease and protect your cat’s body's metabolic rate.
Routine Veterinary Checkups
Routine veterinary medicine is essential to catch potential issues early. Regular physical exams, blood tests, and a complete blood count are critical for monitoring thyroid hormone levels. Early stages of feline hyperthyroidism can be detected through a blood chemistry panel and thyroid scan, allowing for prompt intervention.
Focus on Overall Health
Maintaining your cat's overall health with proper nutrition, exercise, and regular vet care can reduce the risk of heart disease, kidney disease, and other conditions often associated with hyperthyroid cats. A healthy lifestyle can also support kidney function, reduce facial itching, and improve your hyperthyroid cat's life expectancy.